July 26, 2022   USA
diatribe.org: Could There Be a Vaccine for Type 1 Diabetes?
Because GAD-65 is found in the beta cells of the pancreas, auto-antibodies against GAD-65 recognize the protein and damage the beta cells. “What we want to do is re-program the immune system, specifically how it reacts to GAD-65. It’s like a reverse, or therapeutic, vaccine,” said Ulf Hannelius, CEO of Diamyd Medical. “The objective is to change the pro-inflammatory, autoimmune reaction to GAD-65, and to skew that to an anti-inflammatory reaction.”

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