Professor Daniel Kaufman
UCLA School of Medicine, Los Angeles, California, USA. Department of Molecular and Medical Pharmacology.
Professor in Molecular and Medical Pharmacology. Professor Kaufman's research is focused on studies in the field of autoimmunity, particularly type 1 diabetes (T1D) and understanding the disease mechanisms in order to develop novel therapeutics in mouse models that could potentially be translated to clinical use. Using preclinical models, Dr. Kaufman’s lab helped to develop some of the GAD and GABA-based diagnostics and therapeutics for T1D that are in clinical use or are being tested in clinical trials. Professor Kaufman and his lab have recently shown that immune cells have receptors for GABA and that activation of these receptors can inhibit T1D, MS, rheumatoid arthritis, as well as inflammation in type 2 diabetes. In addition, Professor Kaufman and others, have shown that activating GABA receptors on the insulin-producing beta cells can promote the survival and replication of the beta cells. Professor Kaufman has been a member of the Scientific and Medical Advisory Board since 1996.